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Anti-hypertensive sulfonanilide 1 

目录号: HY-U00301
产品使用指南

Anti-hypertensive sulfonanilide 1是有效抗高血压剂,来自专利 EP0338793A2,化合物 XVIIIa,b*,实例1。

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Anti-hypertensive sulfonanilide 1 Chemical Structure

Anti-hypertensive sulfonanilide 1 Chemical Structure

CAS No. : 129280-22-4

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  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-hypertensive sulfonanilide 1 is a potent antihypertensive agent extracted from patent EP0338793A2, compound XVIIIa,b*, example No.1.

体内研究
(In Vivo)

Anti-hypertensive sulfonanilide 1 can be classified as tetralin sulfonanilides, is found to have antihypertensive properties and is therefore useful in controlling elevated blood pressure in mammals such as humans. The effective antihypertensive amount for use will vary both with the route of administration, the condition under treatment and the mammal undergoing treatment, and is ultimately at the discretion of the physician. A suitable oral dose of the active compound for a mammal is in the range of from about 1 to about 50 mg per kilogram body weight per day; preferably from about 2 to about 20 mg/kg[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

424.94

Formula

C20H25ClN2O4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
Animal Administration
[1]

Rats[1]

The blood pressure lowering activities of Anti-hypertensive sulfonanilide 1 is evaluated in conscious, genetically hypertensive rats (300-450 g). The oral doses of Anti-hypertensive sulfonanilide 1 are 3, 10, 30 mg/kg. Systolic and diastolic blood pressure measurements are made directly from the indwelling arterial cannula[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

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产品名称:
Anti-hypertensive sulfonanilide 1
目录号:
HY-U00301
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